What are the dangers of taking amlodipine? (2023)

What are the dangers of taking amlodipine?

Serious side effects

you have stomach problems – severe pain in your stomach, with or without diarrhoea (whether it has blood in it or not), feeling sick and being sick (nausea and vomiting) – these can be signs of pancreatitis.

You will probably need to take amlodipine long-term, even for the rest of your life. Stopping amlodipine may cause your blood pressure to rise. This may increase your risk of heart attack and stroke.

Myth #4: Amlodipine lowers your heart rate

Unlike beta blockers and other calcium channel blockers (like diltiazem and verapamil), amlodipine usually has little to no effect on your heart rate. Amlodipine primarily lowers blood pressure — either alone or in combination with other medications.

Amlodipine oral tablet may cause extreme sleepiness.

Safe medications to use include methyldopa and potentially some diuretics and beta-blockers, including labetalol.

Amlodipine helps to control high blood pressure, angina, and coronary artery disease, but does not cure these conditions. Continue to take amlodipine even if you feel well. Do not stop taking amlodipine without talking to your doctor.

As this study showed, amlodipine itself, as opposed to other CCBs, seems to have better effects with regard to protecting against stroke, ischemic heart disease, and cardiovascular mortality.

Does amlodipine affect vision?

This drug can cause certain eye problems. If left untreated, this can lead to lasting eyesight loss. If eye problems happen, signs like change in eyesight or eye pain most often happen within hours to weeks of starting this drug.

Calcium channel blockers treat high blood pressure. They can decrease bladder contraction, which leads to increased urination. Examples, alone or in combination, include: Norvasc (amlodipine)

Some studies have shown that amlodipine has a protective effect on the kidney.

Elderly blood pressure range for men and women

The American College of Cardiology (ACC) and the American Heart Association (AHA) updated their guidelines in 2017 to recommend men and women who are 65 or older aim for a blood pressure lower than 130/80 mm Hg.

Eight weeks of amlodipine treatment significantly reduced the levels of total cholesterol, low-density lipoprotein cholesterol and triglycerides in the group on the hypercholesterolaemic diet (p < 0.05).

There is no age threshold beyond which hypertension should not be treated. Thiazide diuretics are first-line therapy for isolated systolic hypertension, and they should be considered in any antihypertensive regimen in older persons.

Cause. Edema commonly occurs with calcium channel blockers because the drugs trigger the dilation of blood vessels.

Common side effects may include: muscle or joint pain; diarrhea; nausea, upset stomach; or.

Interactions between your drugs

No interactions were found between amlodipine and Vitamin D3.

It does not matter what time of day you take amlodipine (morning or evening) but it is best to take it at the same time every day, when you are most likely to remember, for more even blood levels and therefore effectiveness. Amlodipine is a calcium channel blocker that dilates blood vessels and improves blood flow.

Does amlodipine raise blood sugar?

Statistical analysis shows a highly significant rise in blood sugar level with 'P' value < 0.001 after 2 and 4 weeks of using 2.5 to 5 mgm (once daily) amlodipine.

You may have constipation while you're taking amlodipine oral tablets. But this wasn't a common side effect in studies of the drug. Constipation can cause symptoms such as: having fewer bowel movements than usual.

The reported chronic gastrointestinal side effects from amlodipine include constipation, dyspepsia, dysphagia, diarrhea, flatulence and pancreatitis.

Mood changes such as depression or anxiety. Difficulty sleeping (insomnia).

While the class of blood pressure-lowering medicines called angiotensin-converting enzyme (ACE) inhibitors may be prescribed more commonly, angiotensin receptor blockers (ARBs) work just as well and may cause fewer side effects.

The two classes of medication are both recommended as "first-line" treatments for high blood pressure: angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs). ACE inhibitors have been around longer and studied more extensively, so doctors prescribe them more often.

Dizziness, lightheadedness, swelling ankles/feet, or flushing may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. To lower your risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Eye Problems Caused by Amlodipine

Whorl keratopathy is an uncommon condition that is almost always a result of medication use. This condition causes damage to the front of the eye and lead to blurred vision and permanently reduced vision.

Can amlodipine cause neuropathy?

Central and Peripheral Nervous System: hypoesthesia, neuropathy peripheral, paresthesia, tremor, vertigo. Gastrointestinal: anorexia, constipation, dysphagia, diarrhea, flatulence, pancreatitis, vomiting, gingival hyperplasia.

ANSWER: Muscle cramps are extremely common in people with or without blood pressure problems, and I have not had a person with cramps that went away on stopping amlodipine. The fact that they came back when you restarted it, however, is pretty strong evidence that the amlodipine may be causing it in you.

GENERALLY AVOID: Coadministration with orange, apple, or grapefruit juice may significantly decrease the oral bioavailability and renin-inhibiting effect of aliskiren.

Amlodipine has an elimination half life of 30 to 50 hours. This is the time it takes for your body to reduce the plasma levels by half. It takes about 5.5 elimination half lives for a medicine to be out of your system. Therefore it'll take about 11.5 days (5.5 x 50 hours = 275 hours) for it to be out from your system.

by Drugs.com

Weight gain with amlodipine may also be a symptom of edema, which is when you retain fluid, which may be particularly noticeable around your ankles or lower legs.

The recalled tablets were packaged in 90-count bottles and distributed to wholesalers and distributors across the U.S. and Puerto Rico from November 2019 to March 2022. Some expiration dates extend into 2024.

The severity of liver injury from amlodipine ranges from mild and transient serum enzyme elevations to self-limited jaundice. Complete recovery is expected after stopping the drug and recovery is usually rapid (4 to 8 weeks). Cases with chronic or fulminant liver injury due to amlodipine have not been reported.

Light-brown or tea-colored urine can be a sign of kidney disease/failure or muscle breakdown.

The new guidelines change nothing if you're younger than 60. But if you're 60 or older, the target has moved up: Your goal is to keep your blood pressure at 150/90 or lower. If you have kidney disease or diabetes, your target used to be 130/80 or lower; now it's 140/90 or lower.

Call 911 or emergency medical services if your blood pressure is 180/120 mm Hg or greater and you have chest pain, shortness of breath, or symptoms of stroke. Stroke symptoms include numbness or tingling, trouble speaking, or changes in vision.

Which number is more important in blood pressure?

Over the years, research has found that both numbers are equally important in monitoring heart health. However, most studies show a greater risk of stroke and heart disease related to higher systolic pressures compared with elevated diastolic pressures.

➢ Pravastatin, fluvastatin or rosuvastatin do not interact with amlodipine. ➢ Atorvastatin (20mg or 40mg daily) is an option if a more potent statin is needed. The risk of an interaction with amlodipine is much lower with atorvastatin than simvastatin. 4.

If you're relying on the drug to keep your blood pressure low or your angina at bay, taking amlodipine every other day won't be often enough, she warns: “While some medications may be taken every other day, the American Heart Association recommends against this practice with blood pressure medications like amlodipine.” ...

Vitamin D deficiency linked to an increased risk for dyslipidemia. Higher vitamin D levels appear to be associated with higher total cholesterol levels and higher HDL cholesterol levels, according to a new study presented at the American College of Cardiology's (ACC) 65th Annual Scientific Sessions.

Safe medications to use include methyldopa and potentially some diuretics and beta-blockers, including labetalol.

Company Announcement. Torrent Pharmaceuticals Limited is voluntarily recalling 14 lots of Valsartan/Amlodipine/HCTZ tablets to the consumer level due to the detection of trace amounts of an unexpected impurity found in an active pharmaceutical ingredient (API) manufactured by Zhejiang Huahai Pharmaceuticals.

Amlodipine helps to control high blood pressure, angina, and coronary artery disease, but does not cure these conditions. Continue to take amlodipine even if you feel well. Do not stop taking amlodipine without talking to your doctor.

Overnight blood pressure control is important in order to lower your risk. If your medication wears off before your next dose is due, your blood pressure may be elevated for several hours while you sleep. You may also wake with high blood pressure. Taking your medication at bedtime may help prevent this issue.

Normal blood pressure for most adults is defined as a systolic pressure of less than 120 and a diastolic pressure of less than 80.

What is a good blood pressure medication with least side effects?

While the class of blood pressure-lowering medicines called angiotensin-converting enzyme (ACE) inhibitors may be prescribed more commonly, angiotensin receptor blockers (ARBs) work just as well and may cause fewer side effects.

The recalled tablets were packaged in 90-count bottles and distributed to wholesalers and distributors across the U.S. and Puerto Rico from November 2019 to March 2022. Some expiration dates extend into 2024.

You may have weight gain while you're taking amlodipine oral tablets. But this wasn't a common side effect in studies of the drug. You may also gain weight if you have edema (swelling), which is a possible side effect of amlodipine oral tablet.

Do not stop taking amlodipine suddenly. Although no "rebound" effect has been reported, it is better to slowly decrease the dosage over a period of time. Your doctor may advise you to take sublingual nitroglycerin for any break-through angina pain.

Amlodipine oral tablet may cause extreme sleepiness.

This drug can cause certain eye problems. If left untreated, this can lead to lasting eyesight loss. If eye problems happen, signs like change in eyesight or eye pain most often happen within hours to weeks of starting this drug. Call your doctor right away if you have these signs.

There is no age threshold beyond which hypertension should not be treated. Thiazide diuretics are first-line therapy for isolated systolic hypertension, and they should be considered in any antihypertensive regimen in older persons.

You can take it at any time of day, but try to make sure it's around the same time every day. You can take amlodipine tablets and liquid with or without food.

Calcium channel blockers treat high blood pressure. They can decrease bladder contraction, which leads to increased urination. Examples, alone or in combination, include: Norvasc (amlodipine)

Cause. Edema commonly occurs with calcium channel blockers because the drugs trigger the dilation of blood vessels.